Mathematical Modeling and Scale-up of Liquid Chromatography by Tingyue Gu
Mathematical Modeling and Scale-up of Liquid Chromatography
Author: Tingyue Gu
Title: Mathematical Modeling and Scale-up of Liquid Chromatography
ISBN10: 3540588841
ISBN13: 978-3540588849
Format: .PDF .EPUB .FB2
Pages:
Publisher: Springer; 1 edition (July 18, 1995)
Language: English
Size pdf: 1828 kb
Size epub: 1297 kb
Rating: 4.0 ✪
Votes: 532
Category: Science & Math
Subcategory: Chemistry
Liquid chromatography has proved to be one of the most important tools for separations. Rapid development in biotechnology has increased the demand for chromatography in analytical, preparative and large scale applications. The understanding of the dynamics of chromatography is imperative for the scale-up. This book is a systematic treatment of the general rate models for various forms of liquid chromatography including adsorption, size exclusion, affinity, reversed phase, hydrophobic interaction, and radial flow chromatography. Thermodynamic and mass transfer effects in liquid chromatography are discussed. Applications of computer programs for the rate models are described and the procedures for the scale-up of preparative- and large-scale liquid chromatography using the general rate models are given.